Care built around you, not a protocol.
An overview of the treatments and approaches Michele uses to help patients across California feel better, age well, and understand what their bodies are actually telling them.
Bioidentical Hormone Replacement (BHRT)
A personalized approach to hormone balance for women navigating perimenopause, menopause, and the years in between.
What it is
Bioidentical hormones are chemically identical to the hormones your body naturally produces. BHRT uses these to support hormone balance during periods of natural change - primarily perimenopause and menopause - when estrogen, progesterone, and testosterone levels shift in ways that affect how women sleep, think, feel, and function.
What it may address
BHRT may be considered when women experience symptoms tied to changing hormone levels - including changes in sleep, mood, cognition, energy, libido, weight regulation, and cycle patterns. Treatment is always evaluated against your symptoms, your medical history, and your comprehensive baseline labs - never based on age or stage alone.
How Michele approaches it
Every BHRT plan at Core Function Health begins with a 60-minute comprehensive consultation and full baseline labs through Quest Diagnostics. Once your labs are back, you and Michele sit down to review every marker together and build a personalized treatment plan. Therapy may include bioidentical estrogen, progesterone, testosterone, thyroid support, longevity therapies, supplements, and lifestyle protocols - every recommendation made only when medically appropriate based on your individual picture.
Available within: the 6-support program and the HRT/TRT Maintenance Program.
Also available for Fee for Service.
Testosterone Replacement Therapy (TRT)
Medically supervised testosterone therapy for men ready to feel like themselves again.
What it is
Testosterone is central to male energy, strength, cognition, mood, and metabolic health - and levels naturally decline with age. TRT restores testosterone to a personalized therapeutic range using medically supervised protocols, with regular labs and treatment adjustments as part of the standard of care.
What it may address
TRT may be considered when men experience symptoms tied to low or suboptimal testosterone levels. As with BHRT, candidacy is evaluated against comprehensive labs, medical history, and a full clinical picture - not numbers alone, and not for every patient.
How Michele approaches it
TRT follows the same care structure as BHRT - a comprehensive consultation, full baseline labs, and a personalized treatment plan reviewed in detail with you. Treatment may include testosterone, thyroid optimization, longevity support, supplements, and lifestyle guidance - adjusted over time as your labs and goals evolve. All prescribing decisions are individualized and made only when medically appropriate.
Available within: the 6-support program and the HRT/TRT Maintenance Program. Also available for Fee for Service. See Programs & Pricing →
Thyroid Optimization
Comprehensive thyroid evaluation that goes beyond a single TSH lab.
What it is
Thyroid health affects energy, weight, mood, cognition, body temperature, hair, skin, and digestion. Standard thyroid screening often relies on TSH alone, which can miss meaningful patterns. Thyroid optimization uses a comprehensive panel - TSH, free T3, free T4, reverse T3, and thyroid antibodies - interpreted against optimal functional ranges, not just standard lab references.
What it may address
A full thyroid evaluation may be appropriate when symptoms suggest thyroid involvement but standard labs have come back "normal," or when patients on existing thyroid medication still don't feel well. Treatment, when indicated, may include thyroid medication adjustments, nutritional and lifestyle support, and ongoing monitoring.
How Michele approaches it
Thyroid evaluation is built into the comprehensive lab work for every patient in the 6-support program. Findings are reviewed alongside the rest of your hormone and metabolic picture - because thyroid rarely operates in isolation.
Available within: the 6-support program and the HRT/TRT Maintenance Program. Also available for Fee for Service.See Programs & Pricing →
"Every treatment recommendation, prescription, and protocol at Core Function Health is individualized. Therapies are offered only when they're medically appropriate and medically necessary, based on your labs, symptoms, history, risk factors, and goals. Not every patient qualifies for every treatment - and that's part of practicing real medicine."
Michele Missakian, PA-C
Medical Weight Management
Sustainable, physician-supervised weight care that treats the underlying picture - not just the scale.
What it is
Medical weight management evaluates weight regulation as a whole-body process - affected by hormones, thyroid function, metabolic health, sleep, stress, nutrition, and lifestyle. Treatment may include medications, longevity therapy, nutritional and lifestyle guidance, and ongoing monitoring, layered together based on what's clinically appropriate.
What it may address
Medical weight management may be a fit when weight has shifted despite consistent effort, when hormone or metabolic factors are suspected, or when patients want clinical oversight of a longevity- or medication-supported approach.
How Michele approaches it
The weight management pathway begins with a focused initial consultation and baseline lab testing. From there, monthly membership care includes a follow-up visit each month, ongoing weight and longevity management support, treatment monitoring, prescription refills when medically appropriate, and quick check-ins between visits.
Available within: the Medical Weight Loss & support program, or integrated into the 6-support program.See Programs & Pricing →
Longevity Therapy
Targeted longevity protocols for recovery, metabolism, healthy aging, and performance - prescribed when clinically appropriate.
What it is
Longevity therapy uses targeted, medically supervised protocols to support recovery, cellular repair, metabolic function, sleep, and healthy aging. At Core Function Health it is integrated into your broader treatment plan rather than offered as a standalone quick fix - always guided by your labs and clinical evaluation.
What it may address
Longevity therapy may be considered for patients interested in recovery and tissue repair, metabolic and weight support, sleep quality, cognitive performance, or healthy aging. As with all therapies, it is recommended only when medically appropriate based on your individual evaluation.
How Michele approaches it
Longevity protocols can be built into the Medical Weight Loss program and incorporated into the 6-month program when clinically relevant. Every recommendation is grounded in your labs, your treatment goals, and your medical history.
Available within: the Medical Weight Loss & support program, or integrated into the 6-support program.See Programs & Pricing →
Functional & Preventive Wellness
Nutritional, lifestyle, and supplement support woven into every treatment plan.
What it is
Hormones, thyroid, weight, and metabolic health don't operate in isolation - they're shaped every day by nutrition, sleep, stress, movement, and supplementation. Functional and preventive wellness strategies integrate these inputs into the medical plan, rather than treating them as an afterthought.
What it may address
Functional and preventive wellness applies to nearly every patient - supporting hormone therapy outcomes, metabolic and weight goals, energy and resilience, gut and digestive health, and long-term aging well.
How Michele approaches it
Every comprehensive plan includes personalized nutrition, lifestyle, and wellness recommendations alongside any prescribed therapy. Supplement guidance is delivered through Fullscript - Michele's preferred professional dispensary - giving you direct, discounted access to high-quality products with personalized recommendations attached to your plan.
Available within: the 6-support program or fee for service.See Programs & Pricing →
Specialty Laboratory Testing
When standard labs don't tell the full story, specialty testing can reveal what's actually driving how you feel. The following advanced options are available when clinically appropriate, at additional cost:
DUTCH Testing
Comprehensive dried urine testing for a complete map of hormone metabolites, cortisol patterns, and organic acids.
GI-MAP
Advanced DNA-based stool testing that provides deep insights into microbial balance, pathogens, and gut inflammation.
Nutreval
Detailed organic acid, amino acid, and nutrient testing evaluating oxidative stress, heavy metals, and mitochondrial function.
Genova Diagnostics Testing
Advanced clinical diagnostic testing targeting gastrointestinal, metabolic, cardiovascular, and endocrine pathways.
SIBO Testing
Specialized lactulose breath testing to confirm or rule out Small Intestinal Bacterial Overgrowth.
4-Point Salivary Cortisol
Multi-point collection tracking adrenal rhythm, biological stress responses, and diurnal cortisol output.
3x4 Genetics
Personalized genomic analysis exploring how genetic pathways influence diet, wellness choices, and health risks.
Specialty testing is recommended only when it adds clinical clarity to your treatment plan - never as a default or upsell.
Frequently Asked Questions
Transparent, direct answers regarding the treatment models and policies at Core Function Health.
That's exactly what the Discovery Call is for. We'll talk through your symptoms and goals to see whether HRT, weight management, functional wellness, or another path makes the most sense as a starting point - and whether Core Function Health is the right fit for you.
No. Core Function Health is a cash-based specialty wellness practice. We do not accept, bill, or participate in any insurance plans. This model allows for personalized, comprehensive care without the limitations of insurance-based medicine.
Yes. In accordance with California medical practice laws, patients must be physically located in California at the time of any appointment.
Not every patient qualifies for every therapy. Treatment recommendations, prescriptions, and protocols are individualized and prescribed only when medically appropriate based on your medical history, symptoms, laboratory findings, risk factors, and Michele's clinical assessment.
No. The cost of prescriptions, supplements, peptides, medications, and specialty laboratory testing is separate from consultation and program fees. This keeps program pricing transparent and lets you opt into only what's clinically appropriate for you.
Ready when you are.
A free 15-minute discovery call. No pressure, no commitment - just a real conversation.
Core Function Health serves patients across California statewide. Cash-pay only. Treatment qualification is determined by clinical labs and medical history evaluation.