Hormone Therapy & Functional Medicine in Orange County
Care built around you, not a protocol.
Personalized hormone therapy, functional medicine, medical weight management, metabolic health, and longevity care for women and men in Seal Beach, Huntington Beach, Long Beach, Orange County, and throughout California.
Bioidentical Hormone Replacement (BHRT)
Personalized bioidentical hormone replacement therapy for women navigating perimenopause and menopause in Orange County and throughout California.
What it is
Bioidentical hormones are chemically identical to the hormones your body naturally produces. BHRT uses these to support hormone balance during periods of natural change - primarily perimenopause and menopause - when estrogen, progesterone, and testosterone levels shift in ways that affect how women sleep, think, feel, and function.
What it may address
BHRT may be considered when women experience symptoms tied to changing hormone levels - including changes in sleep, hot flashes, night sweats, mood, cognition, energy, libido, weight regulation, and cycle patterns. Treatment is always evaluated against your symptoms, your medical history, and your comprehensive baseline labs - never based on age or stage alone.
How Michele approaches it
Every BHRT plan at Core Function Health begins with a 60-minute comprehensive consultation and full baseline labs through Quest Diagnostics. Once your labs are back, you and Michele sit down to review every marker together and build a personalized treatment plan. Therapy may include bioidentical estrogen, progesterone, testosterone, thyroid support, longevity therapies, supplements, and lifestyle protocols - every recommendation made only when medically appropriate based on your individual picture.
Available within the HRT/TRT Maintenance Program and available as Fee for Service.
Testosterone Replacement Therapy (TRT)
Personalized testosterone replacement therapy for men experiencing symptoms of low testosterone.
What it is
Testosterone plays an important role in male energy, strength, cognition, mood, sexual health, body composition, and metabolic health. Testosterone replacement therapy (TRT) may be considered for appropriate men with symptoms and laboratory findings consistent with testosterone deficiency. Treatment is individualized, with regular laboratory monitoring and adjustments when clinically indicated.
What it may address
TRT may be considered when men experience symptoms associated with low testosterone, including low energy, decreased libido, changes in mood or cognition, reduced strength or muscle mass, and changes in body composition. Candidacy is evaluated using symptoms, medical history, comprehensive laboratory testing, and the full clinical picture—not testosterone levels alone.
How Michele approaches it
TRT follows the same care structure as BHRT - a comprehensive consultation, full baseline labs, and a personalized treatment plan reviewed in detail with you. Treatment may include testosterone, thyroid optimization, longevity support, supplements, and lifestyle guidance - adjusted over time as your labs and goals evolve. All prescribing decisions are individualized and made only when medically appropriate.
Available within the HRT/TRT Maintenance Program and available as Fee for Service.
See Programs & Pricing →
Thyroid Optimization
Comprehensive thyroid evaluation that goes beyond a single TSH lab.
What it is
Thyroid health can influence energy, weight regulation, mood, cognition, body temperature, hair, skin, and digestion. Evaluation may extend beyond TSH when clinically appropriate and can include free T4, free T3, thyroid antibodies, and other testing based on symptoms, medical history, and previous results. Laboratory findings are interpreted alongside the complete clinical picture rather than in isolation.
What it may address
A full thyroid evaluation may be appropriate when symptoms suggest thyroid involvement but standard labs have come back "normal," or when patients on existing thyroid medication still don't feel well. Treatment, when indicated, may include thyroid medication adjustments, nutritional and lifestyle support, and ongoing monitoring.
How Michele approaches it
Findings are reviewed alongside the rest of your hormone and metabolic picture - because thyroid rarely operates in isolation.
Available within select care programs or as a fee-for-service option when clinically appropriate. See Programs & Pricing →
"Every treatment recommendation, prescription, and protocol at Core Function Health is individualized. Therapies are offered only when they're medically appropriate and medically necessary, based on your labs, symptoms, history, risk factors, and goals. Not every patient qualifies for every treatment - and that's part of practicing real medicine."
Michele Missakian, PA-C
Medical Weight Management
Sustainable, medically supervised weight management that looks beyond the scale.
What it is
Medical weight management evaluates weight regulation as a whole-body process influenced by hormones, thyroid function, metabolic health, sleep, stress, nutrition, movement, and lifestyle. Treatment is individualized and may include prescription medication when medically appropriate, nutritional and lifestyle guidance, laboratory monitoring, and strategies to support long-term metabolic health.
What it may address
Medical weight management may be a fit when weight has shifted despite consistent effort, when hormone or metabolic factors are suspected, or when patients want clinical oversight of a longevity- or medication-supported approach.
How Michele approaches it
The weight management pathway begins with a focused initial consultation and baseline lab testing. From there, monthly membership care includes a follow-up visit each month, ongoing weight and longevity management support, treatment monitoring, prescription refills when medically appropriate, and quick check-ins between visits.
Available within select care programs or as a fee-for-service option when clinically appropriate.
Longevity Therapy
Personalized longevity and healthy aging strategies designed around your health, labs, and individual goals.
What it is
Longevity care focuses on factors associated with healthy aging, including metabolic health, body composition, sleep, recovery, cardiovascular risk, nutrition, hormone health, and lifestyle. When clinically appropriate, targeted therapies may be incorporated into a broader individualized treatment plan based on your medical history, laboratory findings, risk factors, and goals.
What it may address
Longevity therapy may be considered for patients interested in recovery and tissue repair, metabolic and weight support, sleep quality, cognitive performance, or healthy aging. As with all therapies, it is recommended only when medically appropriate based on your individual evaluation.
How Michele approaches it
Longevity protocols can be built into the Medical Weight Loss program and incorporated into the 6-month program when clinically relevant. Every recommendation is grounded in your labs, your treatment goals, and your medical history.
Available within select care programs or as a fee-for-service option when clinically appropriate.
Functional & Preventive Wellness
Functional medicine-informed nutrition, lifestyle, metabolic health, and supplement support integrated into your treatment plan.
What it is
A functional medicine approach considers how hormones, thyroid health, metabolic health, nutrition, sleep, stress, movement, and digestive health can interact. Rather than viewing each concern in isolation, these factors are considered alongside your medical history, symptoms, laboratory findings, and overall health goals.
What it may address
Functional and preventive wellness applies to nearly every patient - supporting hormone therapy outcomes, metabolic and weight goals, energy and resilience, gut and digestive health, and long-term aging well.
How Michele approaches it
Every comprehensive plan includes personalized nutrition, lifestyle, and wellness recommendations alongside any prescribed therapy. Supplement guidance is delivered through Fullscript - Michele's preferred professional dispensary - giving you direct, discounted access to high-quality products with personalized recommendations attached to your plan.
Available within select care programs or as a fee-for-service option when clinically appropriate.
Specialty Laboratory Testing
When standard laboratory testing doesn't provide the full picture, specialty testing may offer additional information about factors contributing to symptoms or health concerns. The following advanced testing options may be considered when clinically appropriate and are available at additional cost:
DUTCH Testing
Comprehensive dried urine testing for a complete map of hormone metabolites, cortisol patterns, and organic acids.
GI-MAP
Advanced DNA-based stool testing that provides deep insights into microbial balance, pathogens, and gut inflammation.
Nutreval
Detailed organic acid, amino acid, and nutrient testing evaluating oxidative stress, heavy metals, and mitochondrial function.
Genova Diagnostics Testing
Advanced clinical diagnostic testing targeting gastrointestinal, metabolic, cardiovascular, and endocrine pathways.
SIBO Testing
Specialized lactulose breath testing to confirm or rule out Small Intestinal Bacterial Overgrowth.
4-Point Salivary Cortisol
Multi-point collection tracking adrenal rhythm, biological stress responses, and diurnal cortisol output.
3x4 Genetics
Personalized genomic analysis exploring how genetic pathways influence diet, wellness choices, and health risks.
Specialty testing is recommended only when it adds clinical clarity to your treatment plan - never as a default or upsell.
Frequently Asked Questions
Transparent, direct answers regarding the treatment models and policies at Core Function Health.
That's exactly what the Discovery Call is for. We'll talk through your symptoms and goals to see whether HRT, weight management, functional wellness, or another path makes the most sense as a starting point - and whether Core Function Health is the right fit for you.
No. Core Function Health is a cash-based specialty wellness practice. We do not accept, bill, or participate in any insurance plans. This model allows for personalized, comprehensive care without the limitations of insurance-based medicine.
Yes. In accordance with California medical practice laws, patients must be physically located in California at the time of any appointment.
Not every patient qualifies for every therapy. Treatment recommendations, prescriptions, and protocols are individualized and prescribed only when medically appropriate based on your medical history, symptoms, laboratory findings, risk factors, and Michele's clinical assessment.
No. The cost of prescriptions, supplements, medications, and specialty laboratory testing is separate from consultation and program fees. This keeps program pricing transparent and lets you opt into only what's clinically appropriate for you.
Core Function Health is based in Seal Beach, California and serves patients throughout California, including Orange County, Los Angeles County, Huntington Beach, Los Alamitos, Rossmoor, Long Beach, Cypress, Garden Grove, Newport Beach, and surrounding communities.
Ready when you are.
A free 15-minute discovery call. No pressure, no commitment - just a real conversation.
Core Function Health serves patients across California statewide. Cash-pay only. Treatment qualification is determined by clinical labs and medical history evaluation.
Personalized Health Care in Orange County & Throughout California
Core Function Health provides personalized hormone optimization, functional medicine, metabolic health, medical weight management, and longevity care. Our approach looks beyond individual symptoms to help identify patterns, evaluate contributing factors, and develop a personalized plan based on your health history, goals, and individual needs.
Based in Seal Beach, Core Function Health serves patients throughout Orange County, including Huntington Beach, Los Alamitos, Rossmoor, Long Beach, and throughout California.